Pentraxin 3 inhibits fibroblast growth factor 2 induced osteoclastogenesis in rheumatoid arthritis

Pentraxin 3 inhibits fibroblast growth factor 2 induced osteoclastogenesis in rheumatoid arthritis

Background: Synovial fibroblasts (SFs) act as key effector cells mediating synovial inflammation and joint destruction in rheumatoid arthritis (RA). Fibroblast growth factor 2 (FGF2) and its receptors (FGFRs) play important roles in RASF-mediated osteoclastogenesis. Pentraxin 3 (PTX3) is a soluble p...

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Bibliographic Details
Main Authors: Shuai Zhao, Yiteng Wang, Linxin Hou, Yuejiao Wang, Neili Xu, Ning Zhang
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
PTX3
Synovial fibroblasts
FGF2
Osteoclastogenesis
Rheumatoid arthritis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220308210

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http://www.sciencedirect.com/science/article/pii/S0753332220308210

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