Insights in the regulation of trimetylamine N-oxide production using a comparative biomimetic approach suggest a metabolic switch in hibernating bears

Insights in the regulation of trimetylamine N-oxide production using a comparative biomimetic approach suggest a metabolic switch in hibernating bears

Abstract Experimental studies suggest involvement of trimethylamine N-oxide (TMAO) in the aetiology of cardiometabolic diseases and chronic kidney disease (CKD), in part via metabolism of ingested food. Using a comparative biomimetic approach, we have investigated circulating levels of the gut metab...

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Bibliographic Details
Main Authors: Thomas Ebert, Johanna Painer, Peter Bergman, Abdul Rashid Qureshi, Sylvain Giroud, Gabrielle Stalder, Karolina Kublickiene, Frank Göritz, Sebastian Vetter, Claudia Bieber, Ole Fröbert, Jon M. Arnemo, Andreas Zedrosser, Irene Redtenbacher, Paul G. Shiels, Richard J. Johnson, Peter Stenvinkel
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-76346-1

Internet

https://doi.org/10.1038/s41598-020-76346-1

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