Changes in Cerebrospinal Fluid Balance of TNF and TNF Receptors in Naïve Multiple Sclerosis Patients: Early Involvement in Compartmentalised Intrathecal Inflammation

Changes in Cerebrospinal Fluid Balance of TNF and TNF Receptors in Naïve Multiple Sclerosis Patients: Early Involvement in Compartmentalised Intrathecal Inflammation

An imbalance of TNF signalling in the inflammatory milieu generated by meningeal immune cell infiltrates in the subarachnoid space in multiple sclerosis (MS), and its animal model may lead to increased cortical pathology. In order to explore whether this feature may be present from the early stages...

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Bibliographic Details
Main Authors: Roberta Magliozzi, Francesco Pezzini, Mairi Pucci, Stefania Rossi, Francesco Facchiano, Damiano Marastoni, Martina Montagnana, Giuseppe Lippi, Richard Reynolds, Massimiliano Calabrese
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
multiple sclerosis
TNF
cerebrospinal fluid
pathway analysis
inflammation
Online Access:https://www.mdpi.com/2073-4409/10/7/1712

Internet

https://www.mdpi.com/2073-4409/10/7/1712

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