Resistance to Experimental Visceral Leishmaniasis in Mice Infected With Leishmania infantum Requires Batf3

Resistance to Experimental Visceral Leishmaniasis in Mice Infected With Leishmania infantum Requires Batf3

Unveiling the protective immune response to visceral leishmaniasis is critical for a rational design of vaccines aimed at reducing the impact caused by this fatal, if left untreated, vector-borne disease. In this study we sought to determine the role of the basic leucine zipper transcription factor...

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Bibliographic Details
Main Authors: Manuel Soto, Laura Ramírez, José Carlos Solana, Emma C. L. Cook, Elena Hernández-García, Sara Charro-Zanca, Ana Redondo-Urzainqui, Rosa M. Reguera, Rafael Balaña-Fouce, Salvador Iborra
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
Leishmania
Batf3
visceral leishmaniasis
dendritic cells
Batf3 DC+
Th1 responses
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.590934/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.590934/full

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