The impact of empagliflozin on cardiac physiology and fibrosis early after myocardial infarction in non-diabetic rats

The impact of empagliflozin on cardiac physiology and fibrosis early after myocardial infarction in non-diabetic rats

Abstract Background Myocardial fibrosis is a multistep process, which results in collagen deposition in the injured muscle. Empagliflozin, a sodium-glucose cotransporter 2 inhibitor (SGLT2i), decreases cardiovascular events risk. Little is known on the effects of empagliflozin in non-diabetic patien...

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Bibliographic Details
Main Authors: Elias Daud, Offir Ertracht, Nadav Bandel, Gassan Moady, Monah Shehadeh, Tali Reuveni, Shaul Atar
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Cardiovascular Diabetology
Subjects:
Collagen deposition
Empagliflozin
Fibrosis
Myocardial infarction
TGF-β1/Smad3 pathway
Online Access:https://doi.org/10.1186/s12933-021-01322-6

Internet

https://doi.org/10.1186/s12933-021-01322-6

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