The role of C1 inhibitor and complement as acute phase reactants: are we missing the diagnosis of hereditary angioedema?

Abstract Background C1 inhibitor (C1-INH) and complement 4 (C4) have historically been referred to as positive acute phase reactants, however this has never been evaluated in hereditary angioedema (HAE) patients. Low function of C1-INH and low levels of C4 are important in the diagnosis of HAE type...

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Bibliographic Details
Main Authors: Peter Stepaniuk, Ana-Maria Bosonea, Persia Pourshahnazari, Adrienne Roos, Amin Kanani
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Allergy, Asthma & Clinical Immunology
Subjects:
C4
Online Access:https://doi.org/10.1186/s13223-021-00607-5