Elevated MST1 leads to apoptosis via depletion of YAP1 in cardiomyocytes exposed to high glucose

Elevated MST1 leads to apoptosis via depletion of YAP1 in cardiomyocytes exposed to high glucose

Abstract Background Gestational diabetes mellitus is a risk factor for congenital heart defects. The article aimed to investigate the expression and roles of MST1, YAP1, Last1/2 and Survivin in modulating HG-induced cardiomyocyte apoptosis and maternal diabetes-induced heart abnormality. Methods Dia...

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Bibliographic Details
Main Authors: Dongmei Su, Yanhua Li, Lina Guan, Qian Li, Cuige Shi, Xu Ma, Yonghui Song
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Molecular Medicine
Subjects:
High glucose
Cardiomyocyte apoptosis
MST1
YAP1
Survivin
Online Access:https://doi.org/10.1186/s10020-021-00267-6

Internet

https://doi.org/10.1186/s10020-021-00267-6

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