Monocytes, Macrophages, and Metabolic Disease in Atherosclerosis

Atherosclerotic cardiovascular disease (CVD) is a lipid-driven chronic inflammatory disease, in which macrophages are responsible for taking up these lipids and driving disease progression. Over the years, we and others have uncovered key pathways that regulate macrophage number/function and identif...

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Bibliographic Details
Main Authors: Michelle C. Flynn, Gerard Pernes, Man Kit Sam Lee, Prabhakara R. Nagareddy, Andrew J. Murphy
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00666/full