The Physiology and Pathophysiology of T-Tubules in the Heart

The Physiology and Pathophysiology of T-Tubules in the Heart

In cardiomyocytes, invaginations of the sarcolemmal membrane called t-tubules are critically important for triggering contraction by excitation-contraction (EC) coupling. These structures form functional junctions with the sarcoplasmic reticulum (SR), and thereby enable close contact between L-type...

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Bibliographic Details
Main Authors: Ingunn E. Setterberg, Christopher Le, Michael Frisk, Jia Li, William E. Louch
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Physiology
Subjects:
t-tubules
dyad
cardiomyocyte
calcium homeostasis
heart failure
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.718404/full

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https://www.frontiersin.org/articles/10.3389/fphys.2021.718404/full

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