Long-range genomic enrichment, sequencing, and assembly to determine unknown sequences flanking a known microRNA.

Conserved plant microRNAs (miRNAs) modulate important biological processes but little is known about conserved cis-regulatory elements (CREs) surrounding MIRNA genes. We developed a solution-based targeted genomic enrichment methodology to capture, enrich, and sequence flanking genomic regions surro...

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Bibliographic Details
Main Authors: Zhaorong Ma, Michael J Axtell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3869802?pdf=render