Brain cell-derived exosomes in plasma serve as neurodegeneration biomarkers in male cynomolgus monkeys self-administrating oxycodone

Brain cell-derived exosomes in plasma serve as neurodegeneration biomarkers in male cynomolgus monkeys self-administrating oxycodone

Background: The United States is currently facing an opioid crisis. Novel tools to better comprehend dynamic molecular changes in the brain associated with the opioid abuse are limited. Recent studies have suggested the usefulness of plasma exosomes in better understanding CNS disorders. However, no...

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Bibliographic Details
Main Authors: Ashish Kumar, Susy Kim, Yixin Su, Mitu Sharma, Pawan Kumar, Sangeeta Singh, Jingyun Lee, Cristina M. Furdui, Ravi Singh, Fang-Chi Hsu, Jeongchul Kim, Christopher T. Whitlow, Michael A. Nader, Gagan Deep
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:EBioMedicine
Subjects:
Exosomes
Oxycodone
Neuron-derived exosomes
Astrocytes-derived exosomes
Microglia-derived exosomes
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420305685

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http://www.sciencedirect.com/science/article/pii/S2352396420305685

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