The smallest capsid protein mediates binding of the essential tegument protein pp150 to stabilize DNA-containing capsids in human cytomegalovirus.

The smallest capsid protein mediates binding of the essential tegument protein pp150 to stabilize DNA-containing capsids in human cytomegalovirus.

Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus that causes birth defects in newborns and life-threatening complications in immunocompromised individuals. Among all human herpesviruses, HCMV contains a much larger dsDNA genome within a similarly-sized capsid compared to the others, and it w...

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Bibliographic Details
Main Authors: Xinghong Dai, Xuekui Yu, Hao Gong, Xiaohong Jiang, Gerrado Abenes, Hongrong Liu, Sakar Shivakoti, William J Britt, Hua Zhu, Fenyong Liu, Z Hong Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3744435?pdf=render

Internet

http://europepmc.org/articles/PMC3744435?pdf=render

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