Application of MultiStem® allogeneic cells for immunomodulatory therapy: clinical progress and pre-clinical challenges in prophylaxis for graft vs host disease

Application of MultiStem® allogeneic cells for immunomodulatory therapy: clinical progress and pre-clinical challenges in prophylaxis for graft vs host disease

The last decade has seen much progress in adjunctive cell therapy for immune disorders. Both corporate and institutional Phase III studies have been run using mesenchymal stromal cells (MSC) for treatment of Graft vs Host Disease (GvHD), and product approval has been achieved for treatment of pediat...

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Bibliographic Details
Main Authors: Bart eVaes, Wouter eVan 't Hof, Robert eDeans, Jef ePinxteren
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Immunology
Subjects:
Regenerative Medicine
bioreactor
MultiStem
GvHD prophylaxis
adherent stem cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00345/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00345/full

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