Analysis of Myc-induced histone modifications on target chromatin.

The c-myc proto-oncogene is induced by mitogens and is a central regulator of cell growth and differentiation. The c-myc product, Myc, is a transcription factor that binds a multitude of genomic sites, estimated to be over 10-15% of all promoter regions. Target promoters generally pre-exist in an ac...

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Bibliographic Details
Main Authors: Francesca Martinato, Matteo Cesaroni, Bruno Amati, Ernesto Guccione
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2574517?pdf=render