Osthole Enhances Osteogenesis in Osteoblasts by Elevating Transcription Factor Osterix via cAMP/CREB Signaling In Vitro and In Vivo

Osthole Enhances Osteogenesis in Osteoblasts by Elevating Transcription Factor Osterix via cAMP/CREB Signaling In Vitro and In Vivo

Anabolic anti-osteoporotic agents are desirable for treatment and prevention of osteoporosis and fragility fractures. Osthole is a coumarin derivative extracted from the medicinal herbs Cnidium monnieri (L.) Cusson and Angelica pubescens Maxim.f. Osthole has been reported with osteogenic and anti-os...

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Bibliographic Details
Main Authors: Zhong-Rong Zhang, Wing Nang Leung, Gang Li, Siu Kai Kong, Xiong Lu, Yin Mei Wong, Chun Wai Chan
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Nutrients
Subjects:
osthole
osteoblast
osteogenesis
bone regeneration
fracture repair
cAMP/CREB signaling
Online Access:http://www.mdpi.com/2072-6643/9/6/588

Internet

http://www.mdpi.com/2072-6643/9/6/588

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