Prostate Cancer and Bone Metastases: The Underlying Mechanisms

Patients with advanced prostate cancer often develop bone metastases, leading to bone pain, skeletal fracture, and increased mortality. Bone provides a hospitable microenvironment to tumor cells. The disease manifestation is driven by the interaction between invading tumor cells, bone-forming osteob...

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Bibliographic Details
Main Authors: Sok Kuan Wong, Nur-Vaizura Mohamad, Tijjani Rabiu Giaze, Kok-Yong Chin, Norazlina Mohamed, Soelaiman Ima-Nirwana
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/20/10/2587