TGF-β Regulates Collagen Type I Expression in Myoblasts and Myotubes via Transient <i>Ctgf</i> and <i>Fgf-2</i> Expression

TGF-β Regulates Collagen Type I Expression in Myoblasts and Myotubes via Transient <i>Ctgf</i> and <i>Fgf-2</i> Expression

Transforming Growth Factor &#946; (TGF-&#946;) is involved in fibrosis as well as the regulation of muscle mass, and contributes to the progressive pathology of muscle wasting disorders. However, little is known regarding the time-dependent signalling of TGF-&#946; in myoblasts and myotu...

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Bibliographic Details
Main Authors: Michèle M. G. Hillege, Ricardo A. Galli Caro, Carla Offringa, Gerard M. J. de Wit, Richard T. Jaspers, Willem M. H. Hoogaars
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
<i>acvr1b</i>
<i>tgfbr1</i>
myostatin
<i>col1a1</i>
skeletal muscle
fibrosis
myogenesis
atrophy
Online Access:https://www.mdpi.com/2073-4409/9/2/375

Internet

https://www.mdpi.com/2073-4409/9/2/375

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