Evaluation of some aspects in supervised cell type identification for single-cell RNA-seq: classifier, feature selection, and reference construction
Abstract Background Cell type identification is one of the most important questions in single-cell RNA sequencing (scRNA-seq) data analysis. With the accumulation of public scRNA-seq data, supervised cell type identification methods have gained increasing popularity due to better accuracy, robustnes...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-09-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13059-021-02480-2 |