A Set of Global Metabolomic Biomarker Candidates to Predict the Risk of Dry Eye Disease

A Set of Global Metabolomic Biomarker Candidates to Predict the Risk of Dry Eye Disease

PurposeWe used ultraperformance liquid chromatography coupled with quadrupole/time-of-flight tandem mass spectrometry (UPLC-Q/TOF-MS/MS) to analyze the metabolic profile of reflex tears obtained from patients with dry eye disorders.MethodsWe performed a cross-sectional study involving 113 subjects:...

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Bibliographic Details
Main Authors: Yaping Jiang, Chuanxi Yang, Yuxiang Zheng, Yining Liu, Yihui Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
metabolomic
dry eye disease
least absolute shrinkage and selection operator (LASSO) regression
tear profile
glucose metabolism
Glutathione metabolism
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00344/full

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https://www.frontiersin.org/article/10.3389/fcell.2020.00344/full

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