Differential representation of liver proteins in obese human subjects suggests novel biomarkers and promising targets for drug development in obesity

Differential representation of liver proteins in obese human subjects suggests novel biomarkers and promising targets for drug development in obesity

The proteome of liver biopsies from human obese (O) subjects has been compared to those of nonobese (NO) subjects using two-dimensional gel electrophoresis (2-DE). Differentially represented proteins were identified by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spect...

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Bibliographic Details
Main Authors: Simonetta Caira, Antonio Iannelli, Rosaria Sciarrillo, Gianluca Picariello, Giovanni Renzone, Andrea Scaloni, Pietro Addeo
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Obesity
human liver proteome
protein biomarkers
oxidative stress
metabolic syndrome
Online Access:http://dx.doi.org/10.1080/14756366.2017.1292262

Internet

http://dx.doi.org/10.1080/14756366.2017.1292262

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