Genetic association analysis of ATP binding cassette protein family reveals a novel association of ABCB1 genetic variants with epilepsy risk, but not with drug-resistance.

Genetic association analysis of ATP binding cassette protein family reveals a novel association of ABCB1 genetic variants with epilepsy risk, but not with drug-resistance.

Epilepsy constitutes a heterogeneous group of disorders that is characterized by recurrent unprovoked seizures due to widely different etiologies. Multidrug resistance remains a major issue in clinical epileptology, where one third of patients with epilepsy continue to have seizures. Role of efflux...

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Bibliographic Details
Main Authors: Shabeesh Balan, Sumitha Prameela Bharathan, Neetha Nanoth Vellichiramal, Sanish Sathyan, Vijai Joseph, Kurupath Radhakrishnan, Moinak Banerjee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3931716?pdf=render

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http://europepmc.org/articles/PMC3931716?pdf=render

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