Cancer Stem Cells and Neuroblastoma: Characteristics and Therapeutic Targeting Options

The majority of embryonal tumors or childhood blastomas derive from pluripotent progenitors or fetal stem cells that acquire cancer stem cell (CSC) properties: multipotency, self-renewal ability, metastatic potential, chemoresistance, more pronounced levels of drug transporters, enhanced DNA-damage...

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Bibliographic Details
Main Authors: Veronica Veschi, Francesco Verona, Carol J. Thiele
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00782/full