Use of the Tissue Common Rejection Module Score in Kidney Transplant as an Objective Measure of Allograft Inflammation

Use of the Tissue Common Rejection Module Score in Kidney Transplant as an Objective Measure of Allograft Inflammation

Long-term kidney transplant (KT) allograft outcomes have not improved as expected despite a better understanding of rejection and improved immunosuppression. Previous work had validated a computed rejection score, the tissue common rejection module (tCRM), measured by amplification-based assessment...

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Bibliographic Details
Main Authors: Arya Zarinsefat, Jose M. Arreola Guerra, Tara Sigdel, Izabella Damm, Reuben Sarwal, Chitranon Chan-on, Gyula Szabo, Jorge L. Aguilar-Frasco, Xicohtencatl Ixtlapale-Carmona, Carlos Salinas-Ramos, Leonardo Ramirez-Martinez, Claudio Ramirez, Mario Vilatoba, Luis E. Morales Buenrostro, Josefina M. Alberu, Minnie M. Sarwal
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
kidney transplant
acute rejection
biomarkers
transcriptomics
formalin-fixed paraffin-embedded (FFPE)
graft inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.614343/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.614343/full

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