Interaction of the epigenetic integrator UHRF1 with the MYST domain of TIP60 inside the cell

Interaction of the epigenetic integrator UHRF1 with the MYST domain of TIP60 inside the cell

Abstract Background The nuclear epigenetic integrator UHRF1 is known to play a key role with DNMT1 in maintaining the DNA methylation patterns during cell division. Among UHRF1 partners, TIP60 takes part in epigenetic regulations through its acetyltransferase activity. Both proteins are involved in...

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Bibliographic Details
Main Authors: Waseem Ashraf, Christian Bronner, Liliyana Zaayter, Tanveer Ahmad, Ludovic Richert, Mahmoud Alhosin, Abdulkhaleg Ibrahim, Ali Hamiche, Yves Mely, Marc Mousli
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Cancer
Epigenetics
Fluorescence lifetime imaging microscopy (FLIM)
Fluorescence resonance energy transfer (FRET)
Protein-protein interaction
TIP60
Online Access:http://link.springer.com/article/10.1186/s13046-017-0659-1

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http://link.springer.com/article/10.1186/s13046-017-0659-1

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