Nanostructured lipid carriers based suppository for enhanced rectal absorption of ondansetron: In vitro and in vivo evaluations

Nanostructured lipid carriers based suppository for enhanced rectal absorption of ondansetron: In vitro and in vivo evaluations

The current research aimed to fabricate ondansetron nanostructured lipid carriers (OND-NLCs) and incorporate them into a suppository base to manage chemotherapy-induced vomiting and nausea, which offer the advantage of both rapid onset and prolonged release. NLCs were fabricated by adopting the solv...

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Bibliographic Details
Main Authors: Badriyah Shadid Alotaibi, Fahad Pervaiz, Manal Buabeid, Akram Ashames, Khairi Mustafa Fahelelbom, Sana Siddique, Hina Shoukat, Sadia Rehman, Sobia Noreen, Ghulam Murtaza
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Arabian Journal of Chemistry
Subjects:
Nanostructured lipid carriers
Ondansetron
Oleic acid
Lauric acid
Rectal suppository
Emesis
Online Access:http://www.sciencedirect.com/science/article/pii/S187853522100441X

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http://www.sciencedirect.com/science/article/pii/S187853522100441X

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