Multi-cellular human bronchial models exposed to diesel exhaust particles: assessment of inflammation, oxidative stress and macrophage polarization

Multi-cellular human bronchial models exposed to diesel exhaust particles: assessment of inflammation, oxidative stress and macrophage polarization

Abstract Background Diesel exhaust particles (DEP) are a major component of outdoor air pollution. DEP mediated pulmonary effects are plausibly linked to inflammatory and oxidative stress response in which macrophages (MQ), epithelial cells and their cell-cell interaction plays a crucial role. There...

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Bibliographic Details
Main Authors: Jie Ji, Swapna Upadhyay, Xiaomiao Xiong, Maria Malmlöf, Thomas Sandström, Per Gerde, Lena Palmberg
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Particle and Fibre Toxicology
Subjects:
Diesel exhaust particles
Air-liquid interface multicellular model
Inflammation
Macrophage polarization
Oxidative stress
Online Access:http://link.springer.com/article/10.1186/s12989-018-0256-2

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http://link.springer.com/article/10.1186/s12989-018-0256-2

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