Transporters MRP1 and MRP2 Regulate Opposing Inflammatory Signals To Control Transepithelial Neutrophil Migration during Streptococcus pneumoniae Lung Infection

Transporters MRP1 and MRP2 Regulate Opposing Inflammatory Signals To Control Transepithelial Neutrophil Migration during Streptococcus pneumoniae Lung Infection

Streptococcus pneumoniae is a Gram-positive bacterium that normally inhabits the human nasopharynx asymptomatically. However, it is also a major cause of pneumonia, bacteremia, and meningitis. The transition from pneumonia to bacteremia is critical, as patients that develop septicemia have ~20% mort...

Full description

Bibliographic Details
Main Authors: Andrew Zukauskas, Randall J. Mrsny, Paula Cortés Barrantes, Jerrold R. Turner, John M. Leong, Beth A. McCormick
Format: Article
Language:English
Published: American Society for Microbiology 2018-07-01
Series:mSphere
Subjects:
hepoxilin A3
MRP1
MRP2
neutrophil
PMN
Streptococcus pneumoniae
pneumococcus
Online Access:https://doi.org/10.1128/mSphere.00303-18

Internet

https://doi.org/10.1128/mSphere.00303-18

Similar Items