Solubilization of Paclitaxel by Self-Assembled Amphiphilic Phospholipid-Mimetic Polymers with Varied Hydrophobicity

Solubilization of Paclitaxel by Self-Assembled Amphiphilic Phospholipid-Mimetic Polymers with Varied Hydrophobicity

2-Methacryloyloxyethyl phosphorylcholine (MPC) polymers have been used as a coating agent on medical devices and as a carrier in drug delivery systems (DDSs). Paclitaxel (PTX) is a water-insoluble anticancer drug whose solubilizer is necessary for administration. Block and random copolymers composed...

Full description

Bibliographic Details
Main Authors: Chie Kojima, Tomoka Hirose, Risa Katayama, Akikazu Matsumoto
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Polymers
Subjects:
MPC polymer
hydrophobicity
polymer sequence
anticancer drug
solubilization
drug delivery
Online Access:https://www.mdpi.com/2073-4360/13/16/2805

Internet

https://www.mdpi.com/2073-4360/13/16/2805

Similar Items