A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy

The discovery of induced pluripotent stem cells (iPSCs) has created promising new avenues for therapies in regenerative medicine. However, the tumorigenic potential of undifferentiated iPSCs is a major safety concern for clinical translation. To address this issue, we demonstrated the efficacy of su...

Full description

Bibliographic Details
Main Authors: Miki Ando, Toshinobu Nishimura, Satoshi Yamazaki, Tomoyuki Yamaguchi, Ai Kawana-Tachikawa, Tomonari Hayama, Yusuke Nakauchi, Jun Ando, Yasunori Ota, Satoshi Takahashi, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, John J. Miles, Scott R. Burrows, Malcolm K. Brenner, Hiromitsu Nakauchi
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115002179