Synthesis and Biological Evaluation of New Pyridothienopyrimidine Derivatives as Antibacterial Agents and <i>Escherichia coli</i> Topoisomerase II Inhibitors

The growing resistance of bacteria to many antibiotics that have been in use for several decades has generated the need to discover new antibacterial agents with structural features qualifying them to overcome the resistance mechanisms. Thus, novel pyridothienopyrimidine derivatives (<b>2a<...

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Bibliographic Details
Main Authors: Eman M. Mohi El-Deen, Eman A. A. Abd El-Meguid, Eman A. A. Karam, Eman S. S. Nossier, Marwa F. F. Ahmed
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/9/10/695