Age-dependent loss of PTP and LTP in the hippocampus of PrP-null mice

We have investigated synaptic function in the hippocampus in mice of different ages carrying a null mutation in the PrP gene. Experiments carried out in vivo and in vitro in two laboratories revealed no differences in the ability of juvenile and young adult control and PrP-null mice to express long-...

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Bibliographic Details
Main Authors: John Curtis, Mick Errington, Tim Bliss, Karen Voss, Nikki MacLeod
Format: Article
Language:English
Published: Elsevier 2003-06-01
Series:Neurobiology of Disease
Subjects:
LTP
PTP
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103000172