Distinct microRNA expression profile in prostate cancer patients with early clinical failure and the impact of let-7 as prognostic marker in high-risk prostate cancer.

BACKGROUND: The identification of additional prognostic markers to improve risk stratification and to avoid overtreatment is one of the most urgent clinical needs in prostate cancer (PCa). MicroRNAs, being important regulators of gene expression, are promising biomarkers in various cancer entities,...

Full description

Bibliographic Details
Main Authors: Maria Schubert, Martin Spahn, Susanne Kneitz, Claus Jürgen Scholz, Steven Joniau, Philipp Stroebel, Hubertus Riedmiller, Burkhard Kneitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3683014?pdf=render