DNA Methylation as a Biomarker of Treatment Response Variability in Serious Mental Illnesses: A Systematic Review Focused on Bipolar Disorder, Schizophrenia, and Major Depressive Disorder

DNA Methylation as a Biomarker of Treatment Response Variability in Serious Mental Illnesses: A Systematic Review Focused on Bipolar Disorder, Schizophrenia, and Major Depressive Disorder

So far, genetic studies of treatment response in schizophrenia, bipolar disorder, and major depression have returned results with limited clinical utility. A gene × environment interplay has been proposed as a factor influencing not only pathophysiology but also the treatment response. The...

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Bibliographic Details
Main Authors: Charanraj Goud Alladi, Bruno Etain, Frank Bellivier, Cynthia Marie-Claire
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
schizophrenia
bipolar disorder
major depressive disorder
DNA methylation
response variability
Online Access:http://www.mdpi.com/1422-0067/19/10/3026

Internet

http://www.mdpi.com/1422-0067/19/10/3026

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