Long Non-coding RNA LINC00339 Stimulates Glioma Vasculogenic Mimicry Formation by Regulating the miR-539-5p/TWIST1/MMPs Axis

Long Non-coding RNA LINC00339 Stimulates Glioma Vasculogenic Mimicry Formation by Regulating the miR-539-5p/TWIST1/MMPs Axis

Glioma is recognized as a highly angiogenic malignant brain tumor. Vasculogenic mimicry (VM) greatly restricts the therapeutic effect of anti-angiogenic tumor therapy for glioma patients. However, the molecular mechanisms of VM formation in glioma remain unclear. Here, we demonstrated that LINC00339...

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Bibliographic Details
Main Authors: Junqing Guo, Heng Cai, Xiaobai Liu, Jian Zheng, Yunhui Liu, Wei Gong, Jiajia Chen, Zhuo Xi, Yixue Xue
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
glioma
vasculogenic mimicry
LINC00339
miR-539-5p
TWIST1
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253117302950

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http://www.sciencedirect.com/science/article/pii/S2162253117302950

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