The melanoma antigens MELOE-1 and MELOE-2 are translated from a bona fide polycistronic mRNA containing functional IRES sequences.

Our previous studies on melanoma antigens identified two new polypeptides, named MELOE-1 and MELOE-2, that are involved in immunosurveillance. Intriguingly, these antigens are coded by distinct open reading frames (ORF) of the meloe mRNA which is significantly expressed only in the melanocytic linea...

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Bibliographic Details
Main Authors: Delphine Carbonnelle, Virginie Vignard, Delphine Sehedic, Agnes Moreau-Aubry, Laetitia Florenceau, Maud Charpentier, Wolfgang Mikulits, Nathalie Labarriere, François Lang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3783476?pdf=render