Liddle Syndrome: Review of the Literature and Description of a New Case

Liddle Syndrome: Review of the Literature and Description of a New Case

Liddle syndrome is an inherited form of low-renin hypertension, transmitted with an autosomal dominant pattern. The molecular basis of Liddle syndrome resides in germline mutations of the SCNN1A, SCNN1B and SCNN1G genes, encoding the α, β, and γ-subunits of the epithelial Na+ channel (ENaC), respect...

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Bibliographic Details
Main Authors: Martina Tetti, Silvia Monticone, Jacopo Burrello, Patrizia Matarazzo, Franco Veglio, Barbara Pasini, Xavier Jeunemaitre, Paolo Mulatero
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:International Journal of Molecular Sciences
Subjects:
hypertension
hypokalemia
low renin hypertension
monogenic hypertension
Liddle syndrome
SCNN1A
SCNN1B
SCNN1G
Online Access:http://www.mdpi.com/1422-0067/19/3/812

Internet

http://www.mdpi.com/1422-0067/19/3/812

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