Genetics of Proteasome Diseases

The proteasome is a large, multiple subunit complex that is capable of degrading most intracellular proteins. Polymorphisms in proteasome subunits are associated with cardiovascular diseases, diabetes, neurological diseases, and cancer. One polymorphism in the proteasome gene PSMA6 (−8C/G) is associ...

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Bibliographic Details
Main Author: Aldrin V. Gomes
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Scientifica
Online Access:http://dx.doi.org/10.1155/2013/637629