FCγ Chimeric Receptor-Engineered T Cells: Methodology, Advantages, Limitations, and Clinical Relevance

FCγ Chimeric Receptor-Engineered T Cells: Methodology, Advantages, Limitations, and Clinical Relevance

For many years, disappointing results have been generated by many investigations, which have utilized a variety of immunologic strategies to enhance the ability of a patient’s immune system to recognize and eliminate malignant cells. However, in recent years, immunotherapy has been used successfully...

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Bibliographic Details
Main Authors: Giuseppe Sconocchia, Sara Caratelli, Tommaso Sconocchia, Roberto Arriga, Andrea Coppola, Giulia Lanzilli, Davide Lauro, Adriano Venditti, Maria Ilaria Del Principe, Francesco Buccisano, Luca Maurillo, Soldano Ferrone
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Immunology
Subjects:
antitumor activity
chimeric antigen receptor T cells
CD16-CR T cells
CRC
Fc gamma chimeric receptor
hematologic malignancies
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00457/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00457/full

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