Comparison of Depletion Strategies for the Enrichment of Low-Abundance Proteins in Urine.

Proteome analysis of complex biological samples for biomarker identification remains challenging, among others due to the extended range of protein concentrations. High-abundance proteins like albumin or IgG of plasma and urine, may interfere with the detection of potential disease biomarkers. Curre...

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Bibliographic Details
Main Authors: Szymon Filip, Konstantinos Vougas, Jerome Zoidakis, Agnieszka Latosinska, William Mullen, Goce Spasovski, Harald Mischak, Antonia Vlahou, Joachim Jankowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4514849?pdf=render