New genomic structure for prostate cancer specific gene PCA3 within BMCC1: implications for prostate cancer detection and progression.

New genomic structure for prostate cancer specific gene PCA3 within BMCC1: implications for prostate cancer detection and progression.

The prostate cancer antigen 3 (PCA3/DD3) gene is a highly specific biomarker upregulated in prostate cancer (PCa). In order to understand the importance of PCA3 in PCa we investigated the organization and evolution of the PCA3 gene locus.We have employed cDNA synthesis, RTPCR and DNA sequencing to i...

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Bibliographic Details
Main Authors: Raymond A Clarke, Zhongming Zhao, An-Yuan Guo, Kathrein Roper, Linda Teng, Zhi-Ming Fang, Hema Samaratunga, Martin F Lavin, Robert A Gardiner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2655648?pdf=render

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http://europepmc.org/articles/PMC2655648?pdf=render

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