Targeted Sterically Stabilized Phospholipid siRNA Nanomedicine for Hepatic and Renal Fibrosis

Since its discovery, small interfering RNA (siRNA) has been considered a potent tool for modulating gene expression. It has the ability to specifically target proteins via selective degradation of messenger RNA (mRNA) not easily accessed by conventional drugs. Hence, RNA interference (RNAi) therapeu...

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Bibliographic Details
Main Authors: Fatima Khaja, Dulari Jayawardena, Antonina Kuzmis, Hayat Önyüksel
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:Nanomaterials
Subjects:
Online Access:http://www.mdpi.com/2079-4991/6/1/8