Adaptable Model Parameters in Non-Invasive Prenatal Testing Lead to More Stable Predictions

Adaptable Model Parameters in Non-Invasive Prenatal Testing Lead to More Stable Predictions

Recent advances in massively parallel shotgun sequencing opened up new options for affordable non-invasive prenatal testing (NIPT) for fetus aneuploidy from DNA material extracted from maternal plasma. Tests typically compare chromosomal distributions of a tested sample with a control set of healthy...

Full description

Bibliographic Details
Main Authors: Juraj Gazdarica, Jaroslav Budis, Frantisek Duris, Jan Turna, Tomas Szemes
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
non-invasive prenatal testing
statistical models
z-score
Online Access:https://www.mdpi.com/1422-0067/20/14/3414

Internet

https://www.mdpi.com/1422-0067/20/14/3414

Similar Items