Effect of crosslinking agents on chitosan microspheres in controlled release of diclofenac sodium

In this work chitosan microspheres were prepared by the simple coacervation method and crosslinked using epichlorhydrin or glutaraldehyde for the controlled release of diclofenac sodium. The effects of the crosslinking agents on chitosan microspheres over a 12-hour period were assessed with regard t...

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Bibliographic Details
Main Authors: Vanessa L. Gonçalves, Mauro C. M. Laranjeira, Valfredo T. Fávere, Rozângela C. Pedrosa
Format: Article
Language:English
Published: Associação Brasileira de Polímeros 2005-03-01
Series:Polímeros
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282005000100005