Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalisation of NADPH oxidase and nitric oxide synthase in streptozotocin diabetic rats

<p>Abstract</p> <p>Background</p> <p>Nicorandil, an anti-angina agent, reportedly improves outcomes even in angina patients with diabetes. However, the precise mechanism underlying the beneficial effect of nicorandil on diabetic patients has not been examined. We invest...

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Bibliographic Details
Main Authors: Serizawa Ken-ichi, Yogo Kenji, Aizawa Ken, Tashiro Yoshihito, Ishizuka Nobuhiko
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Cardiovascular Diabetology
Subjects:
Online Access:http://www.cardiab.com/content/10/1/105