Inducible ASABF-Type Antimicrobial Peptide from the Sponge Suberites domuncula: Microbicidal and Hemolytic Activity in Vitro and Toxic Effect on Molluscs in Vivo

Inducible ASABF-Type Antimicrobial Peptide from the Sponge Suberites domuncula: Microbicidal and Hemolytic Activity in Vitro and Toxic Effect on Molluscs in Vivo

Since sponges, as typical filter-feeders, are exposed to a high load of attacking prokaryotic and eukaryotic organisms, they are armed with a wide arsenal of antimicrobial/cytostatic low-molecular-weight, non-proteinaceous bioactive compounds. Here we present the first sponge agent belonging to the...

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Bibliographic Details
Main Authors: Werner E. G. Müller, Renato Batel, Heinz C. Schröder, Xiao-Hong Wang, Michael Korzhev, Matthias Wiens
Format: Article
Language:English
Published: MDPI AG 2011-10-01
Series:Marine Drugs
Subjects:
sponges
Suberites domuncula
ASABF
antimicrobial peptides
apoptosis
Bittium sp.
Online Access:http://www.mdpi.com/1660-3397/9/10/1969/

Internet

http://www.mdpi.com/1660-3397/9/10/1969/

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