Propofol Inhibits Cerebellar Parallel Fiber-Purkinje Cell Synaptic Transmission via Activation of Presynaptic GABAB Receptors in vitro in Mice
Propofol is a widely used intravenous sedative-hypnotic agent, which causes rapid and reliable loss of consciousness via activation of γ -aminobutyric acid A (GABAA) receptors. We previously found that propofol inhibited cerebellar Purkinje cells (PC) activity via both GABAA and glycine receptors in...
Main Authors: | Fang-Ling Xuan, Hong-Wei Wang, Li-Xin Cao, Yan-Hua Bing, Chun-Ping Chu, Ri Jin, De-Lai Qiu |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-12-01
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Series: | Frontiers in Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fnins.2018.00922/full |
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