Alpha Enolase 1 Ubiquitination and Degradation Mediated by <i>Ehrlichia chaffeensis</i> TRP120 Disrupts Glycolytic Flux and Promotes Infection

Alpha Enolase 1 Ubiquitination and Degradation Mediated by <i>Ehrlichia chaffeensis</i> TRP120 Disrupts Glycolytic Flux and Promotes Infection

<i>Ehrlichia chaffeensis</i> modulates numerous host cell processes, including gene transcription to promote infection of the mononuclear phagocyte. Modulation of these host cell processes is directed through <i>E. chaffeensis</i> effectors, including TRP120. We previously re...

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Bibliographic Details
Main Authors: Bing Zhu, Jere W. McBride
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pathogens
Subjects:
<i>Ehrlichia</i>
tandem repeat protein
effector
ubiquitin
HECT ligase
α-enolase
Online Access:https://www.mdpi.com/2076-0817/10/8/962

Internet

https://www.mdpi.com/2076-0817/10/8/962

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