IGF-1 and Chondroitinase ABC Augment Nerve Regeneration after Vascularized Composite Limb Allotransplantation.

Impaired nerve regeneration and inadequate recovery of motor and sensory function following peripheral nerve repair remain the most significant hurdles to optimal functional and quality of life outcomes in vascularized tissue allotransplantation (VCA). Neurotherapeutics such as Insulin-like Growth F...

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Bibliographic Details
Main Authors: Nataliya V Kostereva, Yong Wang, Derek R Fletcher, Jignesh V Unadkat, Jonas T Schnider, Chiaki Komatsu, Yang Yang, Donna B Stolz, Michael R Davis, Jan A Plock, Vijay S Gorantla
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4896437?pdf=render