Triazole-Modified Nucleic Acids for the Application in Bioorganic and Medicinal Chemistry

Triazole-Modified Nucleic Acids for the Application in Bioorganic and Medicinal Chemistry

This review covers studies which exploit triazole-modified nucleic acids in the range of chemistry and biology to medicine. The 1,2,3-triazole unit, which is obtained via click chemistry approach, shows valuable and unique properties. For example, it does not occur in nature, constitutes an addition...

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Bibliographic Details
Main Authors: Dagmara Baraniak, Jerzy Boryski
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biomedicines
Subjects:
click chemistry
1,2,3-triazoles
backbone modifications
triazole-linkage
clickable nucleosides and nucleotides
triazole-modified oligonucleotides
Online Access:https://www.mdpi.com/2227-9059/9/6/628

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https://www.mdpi.com/2227-9059/9/6/628

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