Itraconazole Promotes Macrophage M1 Polarization and Phagocytic Capacity of Macrophage to Candida Albicans

Abstract. Objective:. The present study was designed to evaluate whether and how itraconazole affects the macrophage polarization and its reactivity to Candida albicans. Methods:. Cell toxicity of itraconazole was measured using cell counting kit-8 assay in RAW264.7 cells. The cell models were induc...

Full description

Bibliographic Details
Main Authors: Xiao-Li Zheng, Guan-Zhao Liang, Dong-Mei Shi, Hui-Ping Yao, Lu Zhang, Wei-Da Liu, Guan-Zhi Chen
Format: Article
Language:English
Published: Wolters Kluwer Health 2019-12-01
Series:International Journal of Dermatology and Venerology
Online Access:http://journals.lww.com/10.1097/JD9.0000000000000044